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Lorazepam (Ativan) refers to preparations of the benzodiazepine group, its purpose is to treat anxious conditions. Along the way, it removes the excitation of the nervous system, eliminates insomnia, relaxes muscles, helps with convulsions and nausea. The drug is recommended to use no more than four weeks, therapy should be carried out strictly according to the scheme prescribed by the doctor. Since this medicine is addictive, it is necessary to use it in the short-term treatment. You can buy lorazepam online UK without prescription in our online pharmacy.

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Information

Lorazepam has a depressing effect on many structures of the central nervous system associated with the regulation of emotional activity, due to which it exhibits anxiolytic and hypnotic effects. To a lesser extent also has a relaxing effect on the tone of skeletal muscles and anticonvulsant action. Lorazepam is excreted mainly with urine.

Indications

With anxiety disorders of various origin, accompanying diseases of the circulatory system, diseases of the digestive tract; when sleep disturbances are associated with a state of severe anxiety. The states of nervous tension and anxiety associated with the problems of daily life are not an indication for the use of the drug. To avoid complications, the drug must be taken strictly according to the doctor's prescription.

Contraindications

The drug Ativan should not be used in patients with increased sensitivity to benzodiazepines or to any component of the drug, with acute respiratory failure or respiratory center depression, with obsessive thoughts or phobias, as well as in patients with chronic psychoses.

Dosing and Administration

Inside. Tablets are taken three times a day. Dosage at one time should be 1 mg. For a hypnotic effect the drug is applied for half an hour before sleep, the dosage is 1-2 mg. During a state of increased anxiety, excitability, the drug is taken at 6 mg per day. During the premedication, the medication is prescribed one hour before surgery. The dosage of the drug should be 2.5-5 mg. During use with a convulsive syndrome, the drug should be withdrawn slowly. The treatment period with this violation is about a week.

Side effects

From the nervous system and sensory organs: lethargy, fatigue, drowsiness, disorientation, headache, dizziness, depression, ataxia, sleep disturbance, agitation, visual impairment, episodes of amnesia.
On the part of the intestine: dry mouth, nausea, vomiting, diarrhea, changes in appetite.
From the skin: erythema, urticaria.
Other: changes in blood composition (leukopenia), increased LDH activity. Possible development of addiction, drug dependence, withdrawal syndrome, rebound-syndrome.

Interactions

Lorazepam enhances the effect of drugs that depress the central nervous system, including. phenothiazines, narcotic analgesics, barbiturates, antidepressants, hypnotics, anticonvulsant, antihistamines with sedative effect. Potentsiruet action of general and local anesthetics, intensifies the action of curare-like drugs. With simultaneous use with alcohol, in addition to increasing the oppressive effect on the central nervous system, paradoxical reactions are possible (psychomotor agitation, aggressive behavior, a state of pathological intoxication). Nicotine suppresses the activity of lorazepam (accelerates its metabolism).

Special instructions

Use with caution in patients with depression, given the propensity to suicide. In patients with drug and alcohol dependence, use under close supervision of a doctor. Side effects are usually observed at the beginning of therapy. The possibility of more frequent occurrence of side effects in elderly and weakened patients should be considered. During treatment and within 2 days after its termination, it is necessary to exclude the intake of alcoholic beverages; drivers of vehicles and people whose work requires a quick mental and physical reaction, and is also associated with increased concentration of attention, during this period one should not engage in professional activities.

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